Retinoblastoma is a cancer that can occur when the RB1 gene is hypermethylated. RB1 is responsible for stopping progression through the cell cycle between G1 and S phase. Explain how you expect this increased methylation near the RB1 gene to change expression of RB1 and why this might lead to cancer.
The RB1 gene is a tumor suppressor gene, Generally, DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription factor(s) to DNA. Increased methylation near RB1 gene will result in the inhibition of the binding of transcription factor to DNA needed to code for proteins needed for gene suppression in this case, the retinoblastoma protein (pRb).
Indicate which carbons in the deoxyribose sugar are linked to other components of dna.
Complete the sentence with the correct information. One of the big advantages to a 401(k) plan is that ______. a. 401(k) plans are rare enough that they are very valuable
b. the plan automatically increases in value by 500%
c. you don’t have to pay into a 401(k) with your own money
d. the amount you contribute reduces your taxable income
d. reduces your taxes income
When waste and production byproducts are reduced, what is a likely effect? A. expenses are reduced
B. disposal rates go up
C. transportation needs increase
D. expenses are increased
Explanation: When the wastes and by products of the production are reduced then the total expense is reduced in the whole production.
The cost of raw materials are always compared with the cost of the product formed. There must be profit and the expenses will be reduced when there is a comparison between the raw materials and products formed.
If the byproducts are reduced then the whole production cost will also be less.